Showing posts with label india. Show all posts
Showing posts with label india. Show all posts

Friday, 14 October 2016

Register Today for the ACS Symposium in India on Recent Advances in Drug Development, 11-12 November 2016 in Hyderabad, India

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cas

Inaugural ACS Industry Symposium, 11-12 November 2016 in Hyderabad, India

Recent Advances in Drug Development

Register Today for the ACS Symposium in India on Recent Advances in Drug Development
To view this email as a web page, go here.
Register now for the inaugural ACS Industry Symposium, 11-12 November 2016 in Hyderabad, India. Be sure to secure your seat today as rates will increase on 27 October!
The theme of the Symposium is Recent Advances in Drug Development. The event will feature lectures by the world's leading researchers and experts in the pharma industry, including:
  • Dr. Peter Senter of Seattle Genetics
  • Dr. Jagath Reddy Junutula of Cellerant Therapeutics, Inc.
  • Dr. Ming-Wei Wang of the Shanghai Institute of Materia Medica, Chinese Academy of Sciences
This is an exclusive event being organized in partnership with Dr. Reddy's Laboratories for pharma professionals throughout India. Space is limited so register today!
Please visit our website to learn more about the speakers and the program.
Register today to ensure your access to the ACS Industry Symposium. We look forward to seeing you in Hyderabad in November.
CAS
2540 Olentangy River Rd Columbus, OH 43202 US
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/////// ACS Symposium, Recent Advances in Drug Development, 11-12 November 2016, Hyderabad, India, dr reddys, cas

Friday, 6 March 2015

7-allyl-6-hydroxy-indan-1-one...Mom will teach you NMR

Figure US08242291-20120814-C00009


Thermal Claisen rearrangement on 6-allyloxy-indan-1-one,  (III) to obtain 7-allyl-6-hydroxy-indan-1-one, (IV):
  • Formula: C12H12O2
  • Molecular Weight: 188.22200
Synonyms:



http://www.google.com/patents/US8242291
EXAMPLE 2
This example refers to reaction b of the process of the invention.
20 kg of the intermediate of formula (III) prepared as described in example 1 are suspended in 50 l of Dowtherm A under nitrogen flow. In an inert atmosphere, it is heated to approximately 200° C. for approximately 5 hours. Upon completion of the reaction (TLC) a clear red-brown solution is obtained, without the formation of black pitch. The reaction mixture is cooled slowly to 25° C. (a partial precipitation is observed). 100 l (5 volumes) of cyclohexane are added and it is cooled to between 0 and 5° C. for one hour. It is filtered by washing with cyclohexane and dried at reduced pressure and T=45° C. for at least 12 hours. 16.8 kg of yellow solid are obtained which is refluxed in 80 l of toluene in the presence of decolouring carbon. The suspension is filtered, washing it with hot toluene. Part of the solvent is distilled at reduced pressure until the beginning of crystallisation. It is cooled at room temperature and then to between 0 and 5° C. for at least one hour.
The filtered solid is washed with cold toluene and dried at reduced pressure at T=45° C. for at least 12 hours. 15.3 kg of intermediate (IV) are obtained in the form of an almost white solid of quality suitable for continuation of the synthesis.
1H-NMR and mass spectroscopic analyses are performed on part of the product thus obtained, purified by chromatography for analytical purposes (silica gel, 7 parts in volume of heptane—3 parts in volume of ethyl acetate), obtaining the following results:
Electron impact mass: [M+]=188
1H-NMR (500 MHz, CDCl3): δ (ppm)
2.72 ppm, t, J=6 Hz, 2H,  AR C=OCH2 CH2 AR
3.03 ppm, t, J=6 Hz, 2H, AR C=OCH2 CH2 AR
4.03 ppm, d, J=6 Hz, 2H, ARCH2CH=CH2
5.13-5.20, Σd, 2H, ARCH2CH=CH2
5.60 ppm, s, 1H, 0H
5.98-6.10 ppm, m, 1H, CH2CH=CH2
7.13 ppm, d, J=8 Hz, 1H, AR
7.25, d, J=8 Hz, 1H. AR

PREDICT
1H NMR

CLICK ON PICTURE

6-hydroxy-7-prop-2-enyl-2,3-dihydroinden-1-one NMR spectra analysis, Chemical CAS NO. 320574-77-4 NMR spectral analysis, 6-hydroxy-7-prop-2-enyl-2,3-dihydroinden-1-one H-NMR spectrum




13 C NMR

CLICK ON PICTURE


6-hydroxy-7-prop-2-enyl-2,3-dihydroinden-1-one NMR spectra analysis, Chemical CAS NO. 320574-77-4 NMR spectral analysis, 6-hydroxy-7-prop-2-enyl-2,3-dihydroinden-1-one C-NMR spectrum

6-hydroxy-7-prop-2-enyl-2,3-dihydroinden-1-one

COSY PREDICT


HMBC PREDICT

................ 
COCK SAYS MOM CAN TEACH YOU NMR


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Khajuraho Group of Monuments is located in India
Khajuraho Group of Monuments
Location of Khajuraho Group of Monuments in India.

Location in Madhya PradeshLocation in Madhya Pradesh

  1. Khajuraho Group of Monuments - Wikipedia, the free ...

    en.wikipedia.org/wiki/Khajuraho_Group_of_Monuments

    The Khajuraho Group of Monuments are a group of Hindu and Jain temples in Madhya Pradesh, India. About 620 kilometres (385 mi) southeast of New Delhi, ...























Hotel Chandela - A Taj Leisure Hotel







Sunday, 3 August 2014

1- Methyl cyclohexene, All about it pictoral




reactions of .above


CAS NO : 1335-86-0
EC NO : 215-640-8
Molecular Formula : C7H12
Main Specifications :
Synonyms : Methyl-1-cyclohexene;1-methylcyclohexene;
1-Methyl-cyclohexene
Molecular Structure:1-Methyl-cyclohexene 1335-86-0




  • Reactants:
    • 2-methylcyclohexan-1-ol
  • Product:
    • 1-methylcyclohexene
  • Type of Reaction:
    • Alkene formation via dehydration






IR



NMR spectrum of 1-methyl-1-cyclohexene.

Source: Spectral Database for Organic Compounds SDBS        http://www.aist.go.jp/RIODB/SDBS/cgi-bin/cre_index.cgi
Assign   Shift(ppm)
  A       5.379
  B       1.96
  C       1.89
  D       1.627
  E       1.61
  F       1.54













Individual Reactions

Hydrogen + Cyclohexene, 1-methyl- = Cyclohexane, methyl-
By formula: H2 + C7H12 = C7H14
QuantityValueUnitsMethodReferenceComment
Δr-111.4 ± 0.37kJ/molChydRogers, Crooks, et al., 1987liquid phase
Δr-106.3 ± 0.46kJ/molChydTurner and Garner, 1958liquid phase; solvent: Acetic acid
Δr-106.3 ± 0.46kJ/molChydTurner and Garner, 1957liquid phase; solvent: Acetic acid

Cyclohexene, 1-methyl- + Trifluoroacetic acid = C9H13F3O3
By formula: C7H12 + C2HF3O2 = C9H13F3O3
QuantityValueUnitsMethodReferenceComment
Δr-36.56 ± 0.88kJ/molCacWiberg, Wasserman, et al., 1985liquid phase; solvent: Trifluoroacetic acid; Trifluoroacetolysis

Cyclohexene, 1-methyl- + Hydrogen chloride = 1-Chloro-1-methylcyclohexane
By formula: C7H12 + HCl = C7H13Cl
QuantityValueUnitsMethodReferenceComment
Δr-56.11 ± 0.88kJ/molCmArnett and Pienta, 1980liquid phase; solvent: Methylene chloride; Hydrochlorination

Cyclohexane, methylene- = Cyclohexene, 1-methyl-
By formula: C7H12 = C7H12
QuantityValueUnitsMethodReferenceComment
Δr-7.2 ± 0.3kJ/molEqkYursha, Kabo, et al., 1974gas phase; Heat of isomerization at 463 K

Cyclohexene, 3-methyl- = Cyclohexene, 1-methyl-
By formula: C7H12 = C7H12
QuantityValueUnitsMethodReferenceComment
Δr-8.1 ± 0.3kJ/molEqkYursha, Kabo, et al., 1974gas phase; Heat of isomerization at 463 K

Cyclohexene, 4-methyl- = Cyclohexene, 1-methyl-
By formula: C7H12 = C7H12
QuantityValueUnitsMethodReferenceComment
Δr-5.8 ± 0.3kJ/molEqkYursha, Kabo, et al., 1974gas phase; Heat of isomerization at 463 K









Alleppey kerala.....Alappuzha

Alappuzha - Wikipedia, the free encyclopedia

en.wikipedia.org/wiki/Alappuzha
pronunciation (help·info)), also known as Alleppey, is the administrative headquarters of Alappuzha District of Kerala state of southern India. Alappuzha is the ...
 
 
 
 
 
Map of alleppey.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Table in restaurant after eating fish, Alleppey, Kerala, India, South Asia,
 
 
 
 
 
 
 
 
 
 
 
 
 
 PAGODA RESORTS ALLEPPEY KERALA INDIA
 
 
 
 
 
 
 

 
 
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